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    Reader Question on Lamictal (Lamotrigine)

    Hi Julie,

    I just read all the blogs and comments on Lamictal (and the generic Lamotrigine) and they really answered a lot of questions for me. First off, and I know you’re not supposed to do this, but my daughter had some left over meds when she tried it, so I used those up before I refilled my prescription. I noticed a couple of different things that happened to me while taking her prescription, but I blew them off not even thinking about them until I read the blogs. The first one was a twitch I got in my left hand when using the computer mouse and the second one is the rash that I got on my chest just above the breast. I am very thankful that you talk so much about Lamictal side effects. The only thing is these symptoms didn’t show up until I used my daughter’s prescription. Could it have been because of the age of the pills? Everything else about them is the same as mine. I just wasn’t sure if there is an expiration date on them or not but this is my only explanation of these 2 symptoms. What do you  think?

    Tamara

    Hi Tamara,

    It’s always best to talk with your doctor regarding the Stevens Johnson Syndrome rash.  It’s serious, but very few people on Lamictal get this rash.  I know of one person who had to stop the drug out of the hundreds of people I know who take Lamictal. The rash is usually  benign and can be treated with benadryl.  Definitely call your doctor though and give an update.

    I have to stress that a mild rash is very normal. A rash that really itches with oozing sores like poison ivy is not ok! It’s estimated that .3 % get the rash. That’s a very small number compared to the lives saved by Lamictal.

    You do not have to stop Lamictal/Lamotrigine if you get the rash. It may just mean your dose is too high at first. Lamictal is started slowly in order to prevent the rash. Then if you go up in dose and it shows up, you can go back down and slowly go up again. Your health care professional will know all about this.

    I still get some itching from the Lamical, but I live with it.  My coauthor Dr. John Preston is my source of info, so I’m lucky I can call him with all of my questions and he mentioned that most of the rashes are benign.

    Remember, I am not a medical doctor!

    As for the twitching- you should see me when it really gets going! It’s pretty comical. It’s very uncomfortable- especially in the legs. I know it means my dose is too low.  So twitching is not uncommon, but it shouldn’t last.

    Regarding taking your daughter’s pills, I use my mom’s pills if I forget mine. She is on Lamictal as well.  Lot’s of people do this.

    I know that doctors say not to do this- and I am NOT saying to do this, but reality is reality.I say it’s a lot better to take what is there than to go without! Also, to throw out expensive pills simply makes no sense.  I tell my nurse practitioner what I am going to do and she is supportive in these kinds of situations.

    The age of the Lamictal is a question you can ask you doctor or pharmacist- but I doubt it is too old if it’s a semi recent prescription. If you switched between regular and generic that may be the problem. As you may have read in my other posts- generic Lamictal (Lamotrigine) did not work for me. The twitching side effects were quite intense. Once I switched back to Lamictal I was better.  This is beacuse the way they make the pills can be different and we absorb the drugs differently. I write a lot about this on the blog under the term ‘generics.’

    I love Lamictal as you know. My coauthor John says it’s the most effective bipolar depression drug with the least side effects.

    Thanks for your question and definitely check in with your doctor about the rash if it continues, spreads or oozes! If not, you should be fine.

    Julie

     

    PS: There is an excellent comment from Heidi in the comments section.

    Related posts:   Reader Question: Lamictal dosage (lamotrigine) |  Bipolar Meds: Lamictal (Lamotrigine) side effects |  Reader Question: Lamictal doses |





    4 comments to Reader Question on Lamictal (Lamotrigine)

    • Noelle Marier
      January 14, 2009 at 5:06 pm · Reply to this comment

      Is that why I’m itchy? I have a lot of allergies and without my allergy medication I get hives. I’ve never had the rash, but I do feel a lot more itchy while on Lamictal than I used to…I hadn’t heard that was a side effect before. Unfortunately, sometimes it’s hard to go to sleep because I keep getting little itchies all over! Oh well, the benefits of the drug outweigh the problems, I think.

      Thanks, Julie!

      Hi Noelle,

      Oh yes, Lamictal can cause all kinds of itchiness! It can be external like the rash, but it can also be internal. It feels like some kind of little squiggly thing is crawling under your skin! I have not had it lately, but it was pretty bad a few months ago. My side effects since starting generic Lamictal are bad twitching and leg pain. I’ve actually had those a lot in the past, but the generic has really exacerbated them! I agree that the Lamictal is totally worth these side effects. I find that they get better over time and only flare up when I forget a dose. Julie

    • Ted Thieman
      January 14, 2009 at 9:12 pm · Reply to this comment

      Hey Julie:

      I was taking generic lamictol for 4 weeks during December, but around Christmas the side effects-headache,anxiety-became too much on 50mg. I know you’re not a doctor, but in your experience do these subside over time. I’m a street musician in Portland and just getting turned on to your bi-polar crusade. Your work looks pretty amazing.

      Regards,

      Ted

    • Heidi Ransom
      May 4, 2012 at 5:34 pm · Reply to this comment

      I was put on Lamictal during a hospitalization for severe depression and within a week I had A rash from hell! I literally could not stop scratching for more than 2 minutes at a time. My skin was weeping and felt like leather. My family doctor took me off of it and the rash went away. It was a rash I will never ever forget.

    • Julie Fast
      May 6, 2012 at 10:21 am · Reply to this comment

      Hello Heidi,

      The Stephen’s Johnson rash is very, very rare- but it does happen. I’ve seen it up close and it looks like weepy poison ivy. Here is some more information:

      In adults, a dangerous Lamictal rash seems to be a little less common. Up to 0.3 percent of adults taking the drug developed a rash that required hospitalization. The rashes were less common in people taking it for bipolar disorder and were more likely in people taking Lamictal for epilepsy. Just like with children, combining Lamictal with divalproex (Depakote, Depakote ER) or valproic acid (Depakene) increased the risk of serious rashes (up to 1 percent).

      These risks are much smaller and less dangerous than a severe depression in my opinion!

      Thanks for your comment. I’m sorry you got the rash and I am glad you are better.

      Julie

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