Reader Question:The Bipolar Antipsychotic and Weight Gain Dilemma

Here is a question about the antipsychotic Seroquel and weight gain.

Hi Julie,

I have been on Seroquel for over 5 years now. I have Bipolar with psychosis. I am tired of the weight gain fight. Seroquel has been very affective in controlling the psychosis which I have frequently. Is there anything that can replace the Seroquel in controlling the psychosis without the weight gain?

Stinker

Hi There Stinker,

Here is a short answer to your question:

Maybe.

Everyone responds differently to antipsychotics.  Most gain wait on them,but some don’t. It’s very,very well documented for example that Zyprexa has an average 20 lb weight gain.  Seroquel,Risperdal,and the other atypical antipsychotics are known for weight gain around the stomach. This leads to a complication called Metabolic Syndrome- I wrote quite a great article on this last year for www.healthyplace.com if you want to read more about it. Just type in Julie Fast [ Read More ]





FDA Approved Bipolar Disorder Drugs

Here is an interesting list- the FDA (federal drug administration) has to ok a drug for use with bipolar disorder before a drug company can advertise that the drug can be used for bipolar disorder. Here is a list of the approved drugs with their initiation dates. I will write more on this topic in the next few days:

FDA:Acute Mania        *   1970:  Lithium       *   1973:  Thorazine        *   1995:  Depakote       *   2000:  Zyprexa           *   2003:  Risperdal         *   2004:  Seroquel       *   2004:  Abilify       *   2005:  Geodon       *   2005:  Equetro (Tegretol)     FDA:Acute Bipolar Depression             *  2004:Symbyax                  (Prozac-Zyprexa combo)          *  2007:Seroquel

FDA:Maintenance (for use in managing bipolar disorder in general)                *  1974:  Lithium:both          *  2003:  Lamictal:                         depression          *  2004:  Zyprexa:both          *  2005:  Abilify:both

This list can be a bit confusing- especially [ Read More ]





Bipolar Disorder Medications:What is Zyprexa? (Olanzapine)

 Zyprexa,also known as Olanzapine is an anti psychotic drug (also known as a neuroleptic) used to treat psychosis and psychotic mania.

It’s called an atypical antipsychotic as it is a new class of drugs with less side effects that the old anti-psychotics such as Thorazine and Haldol. Zyprexa is known for weight gain- an average of 20 pounds per person,but I definitely know people who don’t gain weight at all.

Zyprexa is used to treat bipolar disorder mania and psychosis – (and schizophrenia.)

I have seen it work miracles on people who are very ill.  It’s hard to find a balance between the benefits of the drug and the side effects- but for many,the benefits are what matters. I have a friend who was on the drug for two years to keep her mania and psychosis in check. It definitely kept her out of the hospital- but she felt over drugged and [ Read More ]





Bipolar Disorder and Pristiq (desvenlafaxine):a new antidepressant

I recently opened a magazine and saw an antidepressant (Pristiq) I had never heard of- so I asked my coauthor Dr. John Preston to explain the mistique of Pristiq!

Hi…Pristiq (desvenlafaxine)is a clone of Effexor…I like it because the starting dose is often the therapeutic dose (50 mg)…with Effexor you had to start low (37.5 mg) and gradually increase the dose (often up to 150-300 mg)…also Pristiq has somewhat less nausea than Effexor….but like all antidepressants is absolutely can cause mania…John 

**And as we all know…people with bipolar disorder can’t take antidepressants alone- and if they do take them- it needs to be in combination with a mood stabilizer such as lithium,depakote or tegretol!  Pristiq sounds like a resort! Who names these things!  Julie  

PS:If you view this blog from amazon.com,you can see the whole blog at www.bipolarhappens.com/bhblog

[ Read More ]





Abilify and Bipolar Disorder:Reader Question

Hi Julie,

Recently,my daughter switched from Risperdal to Abilify. I am hoping Abilify will be good for her,contrary to what I have heard. Do you have any information regarding the success of bipolar people on Abilify? T.

Hi T.

Risperdal and Abilify are anti psychotic drugs. They are often used in the treatment of bipolar disorder. If a person is really manic or psychotic and has to go to the hospital,anti psychotic are often use to get the person to come down from the mania and psychosis. The dose is often very high. When my partner Ivan was so sick in 1994,he was immediately put on anti psychotics and mood stabilizers just to get him out of the mania,so this is common.

What a person takes depends on their symptoms. Many people with bipolar disorder do well on a mood stabilizer such as Lithium. I do well on a depression,[ Read More ]





Bipolar Manic/Psychotic Talk

Manic/Psychotic Talk

“He blew a glass jacket. The walls were mayo and I was chewing all of the dirt off of the vegetables.”

The above is known as a word salad ( no pun intended!) –the sayings are close enough for us to understand them – but overall,they just make no sense.

A psychotic friend of mine said the above during an episode.

Psychosis is a fascinating topic- it’s horrible to experience and horrific to see someone go through it- I have been through both.  But after it is over,you can certainly be fascinated by what was said.

Julie